| DAT | MOTSTÅNDARE | RESULTAT | MÅLGÖRARE | pl | |
| 8 aug | We | MANCHESTER UTD - CS | 1-3 |
(Valencia 41, Hernandez 76, Berbatov 90+2) Kalou 83 |
- |
| 14 | H | WEST BROMWICH | 6-0 | Malouda 6,90+1, Drogba 45+1, 55, 68, Lampard 63 | 1 |
| 21 | b | Wigan | 6-0 | Malouda 34, Anelka 48, 52, Kalou 78, 90, Benayoun 90+4 | 1 |
| 28 | H | STOKE | 2-0 | (straffmiss Lamps 11) Malouda 32, Drogba 77 str | 1 |
| 11 sep | b | West Ham | 3-1 | Essien 2, 83 Kalou 17 (Parker 85) | 1 |
| 15 | b | MSK Zilina - CL | 4-1 | Essien 13, Anelka 24, 28, Sturridge 48 (Oravec 55) | 1 |
| 19 | H | BLACKPOOL | 4-0 | Kalou 2, Malouda 12, 41 självmål Evatt 30 | 1 |
| 22 | H | NEWCASTLE - CC | 3-4 | van Aanholt 6, Anelka 7, 86 str (Ranger 27, Taylo 33, Ameobi 4, 90) (2 skador, 30 min 10 man) | - |
| 25 | b | Manchester City | 0-1 | (Tevez 59) | 1 |
| 28 | H | MARSEILLE - CL | 2-0 | Terry 7, Anelka 28 | 1 |
| 3 okt | H | ARSENAL | 2-0 | Drpgba 39, Alex 85 | 1 |
| 16 | b | Aston Villa | 0-0 | 1 | |
| 19 | b | Spartak Moskva - CL | 2-0 | Zhirkov 24, Anelka 43 | 1 |
| 23 | H | WOLVERHAMPTON | 2-0 | Malouda 23, Kalou 81 | 1 |
| 30 | b | Blackburn | 2-1 | (Benjani 22) Anelka 39. Ivanovic 84 | 1 |
| 3 nov | H | SPARTAK MOSKVA - CL | 4-1 | Anelka 49, Drogba 62 str, Ivanovic 6, 90+2 6 (Bazhenoz 86) | 1 |
| 7 | b | Liverpool | 0-2 | (Torres 12, 45) | 1 |
10 |
H | FULHAM | 1-0 | Essien 30 //Essien utv 90+2// | 1 |
| 14 | H | SUNDERLAND | 0-3 | (Onuoha 45, Gyan 52, Wellbeck 87) | 1 |
| 20 | b | Birmingham | 0-1 | (Bowyer 16) | 1 |
| 23 | H | MSK ZILINA - CL | 2-1 | ( B Bello 19) Sturridge 51, Malouda 86 | 1 |
| 28 | b | Newcastle | 1-1 | (Carroll 6) Kalou 45 | 2 |
| 4 dec | H | EVERTON | 1-1 | Drogba 42 str, (Beckford 86) | 3 |
| 8 | b | Marseille - CL | 0-1 | (Brandao 81) | 1 |
| 11 | b | Tottenham | 1-1 | (Pavlyuchenko 15) Drogba 70, Drogba missade straff 90+2 | 4 |
| 26 | b | Arsenal | 1-3 | (Song 44, Fabregas 51, Walcott 53) Ivanovic 57 | 4 |
| 28 | H | BOLTON | 1-0 | Malouda 61 | 4 |
| 2011 2 jan |
H | ASTON VILLA | 3-3 | Lampard 22 str, Drogba 8, Terry 894 (A Young 41 str. Heskey 47, Clark 90+1) | 5 |
| 4 | b | Wolverhampton | 0-1 | (självmål Bosingwa 5) | 5 |
| 9 | H | IPSWICH - FA 3 | 7-0 | Kalou 33, Sturridge 33, 52, självmål Edwards 41, Anelka 52, Lampard 78, 79 | - |
| 15 | H | BLACKBURN | 2-0 | Ivanovic 57, Anelka 76 | 4 |
| 24 | b | Bolton | 4-0 | Drogba 11, Malouda 41, Anelka 56, Ramires 74 | 4 |
| 30 | b | Everton- FA 4 | 1-1 | (Saha 62) Kalou 75 | - |
| 1 feb | b | Sunderland | 4-2 | (Bardsley 4, Richardson 26) Lampard 15 str, Kalou 23, Terry 60, Anelka 90+3 | 4 |
| 6 | H | LIVERPOOL | 0-1 | (Meireles 69) | 4 |
| 12 | b | Fulham | 0-0 | 5 | |
| 19 | H | EVERTON - FA 4 omspel | 1-1 e förl 3-4 e str | Lampard 104 (Baiens 119) (Anelka, Cole missade sina straffar) | - |
| 22 | b | FC København FCK - CL 8-del | 2-0 | Anelka 17, 54 | - |
| 1 mars | H | MANCHESTER UNITED | 2-1 | (Rooney 30) Luiz 54, Lampard 79 str | 4 |
| 7 | b | Blackpool | 3-1 | Terry 20, Lampard 62 str, 66 (Puncheon 86) | 4 |
| 16 | H | FC KØBENHAVN - CL 8-del | 0-0 | - | |
| 20 | H | MANCHESTER CITY | 2-0 | Luiz 78, Ramires 90+2 | 3 |
| 2 apr | b | Stoke | 1-1 | (Walters 8) Drogba 33 | 3 |
| 6 | H | MANCHESTER UNITED - CL QF | 0-1 | (Rooney 24) | - |
| 9 | H | WIGAN | 1-0 | Malouda 67 | 3 |
| 12 | b | Manchester United - CL QF | 1-2 | (Hernandez 43, Park 77) //Ramires utvisad, 2 gula, andra hårt, 71 // Drogba 76 | - |
| 16 | b | West Bromwich | 3-1 | (Odemwingie 17) Drogba 22, Kalou 26, Lampard 44 | 3 |
| 20 | H | BIRMINGHAM | 3-1 | Malouda 3, 62, Kalou 26 (Larsson 77 str) | 2 |
| 23 | H | WEST HAM | 3-0 | Lampard 44, Torres 84, Malouda 90+3 | 2 |
| 30 | H | TOTTENHAM | 2-1 | (Sandro 19) Lampard 45, Kalou 89 | 2 |
| 8 maj | b | Manchester United | 1-2 | (Hernandez 1, Vidic 23) Lampard 69 | 2 |
| 15 | H | NEWCASTLE | 2-2 | Ivanovic 2, Alex 82 ( Gutierrez 10, Taylor 90+3) | 2 |
| 22 | b | Everton | 0-1 | (Beckford 75) //Coleman utv 52 | 2 |